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Amylin, also known as islet amyloid polypeptide (IAPP), is a 37-amino acid peptide hormone that is co-secreted with insulin from pancreatic beta cells in response to nutrient intake, particularly meals containing glucose and amino acids

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However, when mast cells trigger too easily, they degranulate and release a payload of histamine, heparin, prostaglandins, tryptase, and cytokines into the body too frequently